Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish.

Scientific reports - 23 Jun 2020

Weaver Megan L, Piedade Warlen P, Meshram Nishita N, Famulski Jakub K

Abstract excerpt

Vertebrate retinal development requires timely and precise fusion of the optic fissure (OF). Failure of this event leads to congenital vision impairment in the form of coloboma. Recent studies have suggested hyaloid vasculature to be involved in OF fusion. In order to examine this link, we analyzed OF fusion and hyaloid vasculogenesis in the zebrafish pax2a noi mutant line. We first determined that pax2a-/-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basement Membrane
Share to Coloboma
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Matrix Metalloproteinase 2

Share to PAX2 Transcription Factor

Share to Retina

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 32576859
DOI: 10.1038/s41598-020-66451-6
PMCID: PMC7311462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish.PMID 32576859Read ↗

Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos.Semantic proximity Read ↗

Transcriptome profiling of zebrafish optic fissure fusionSemantic proximity Read ↗

Regional Gene Expression Profile Comparison Reveals the Unique Transcriptome of the Optic FissureSemantic proximity Read ↗

Detailed analysis of chick optic fissure closure reveals Netrin-1 as an essential and conserved mediator of epithelial fusion during vertebrate embryogenesisSemantic proximity Read ↗

TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonismSemantic proximity Read ↗

Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closureSemantic proximity Read ↗

Reversal of vein of Galen aneurysmal malformation by stimulation of flow-mediated vessel fusionSemantic proximity Read ↗

Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure.Semantic proximity Read ↗

Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover.Semantic proximity Read ↗

Anatomy of the complete mouse eye vasculature in development and pathology explored by light-sheet fluorescence microscopySemantic proximity Read ↗

Cerebral Vein Malformations Result from Loss of Twist1 Expression and BMP Signaling from Skull Progenitor Cells and Dura.Semantic proximity Read ↗

Candidate gene approach identifies multiple genes and signaling pathways downstream of Tbx4 in the developing allantois.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.