Article
[Clinical and immunological characteristics of hiv-infection in patients with Asp299glly polymorphism of the Toll-like receptor 4 gene].
Georgian medical news - 1 Nov 2013
Kirichenko T S, Koval' T I, Kaĭdashev I P, Dubinskaia G M
Abstract excerpt
The prevalence of Asp299Gly polymorphism of the TLR4 gene and its impact on the clinical and immunological characteristics of HIV infection were investigated. Asp299Gly polymorphism of the TLR4 gene was observed significantly in HIV-infected patients - 12.0 % as compared with controls (2.1%, p<0,05). This study suggests a greater risk for development of viral, bacterial and parasitic infections in HIV- positive...
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