Article
Susceptibility to HIV-1 infection is influenced by toll like receptor-2 (-196 to -174) polymorphism in a north Indian population.
The journal of gene medicine - 1 Aug 2017
Vidyant Sanjukta, Chatterjee Animesh, Agarwal Vikas, Dhole Tapan N
Abstract excerpt
BACKGROUND: Toll like receptors (TLRs) are pattern recognition receptors that recognize molecular patterns of pathogens and play an important role in innate immunity. Recent studies have identified that a single nucleotide polymorphism (SNP) in the TLR gene impairs the response to TLR ligands in some individuals and is associated with susceptibility to various infectious diseases. The present study aimed to...
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