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Toll-Like Receptor Genes and Risk of Latent Tuberculosis Infection in People Infected with HIV-1.

Viruses - 28 Aug 2024

Salamaikina Svetlana, Kulabukhova Ekaterina, Korchagin Vitaly, Khokhlova Olga, Mironov Konstantin, Akimkin Vasiliy

Abstract excerpt

The purpose of this study was to determine the contribution of genetic factors, i.e., the level of expression and polymorphisms of Toll-like receptors (TLR), to the susceptibility of latent tuberculosis infection in a Russian cohort of individuals infected with HIV. The patients (n = 317) with confirmed HIV infection were divided into two groups according to the results of the STANDARD E TB-Feron test: 63 cases...

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Identifiers

PMID: 39339847
DOI: 10.3390/v16091371
PMCID: PMC11436194

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