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Article

Antirestriction Protein ArdB (R64) Interacts with DNA.

Biochemistry. Biokhimiia - 1 Mar 2020

Kudryavtseva A A, Okhrimenko I S, Didina V S, Zavilgelsky G B, Manukhov I V

Abstract excerpt

The antirestriction ArdB protein inhibits the endonuclease activity of type I restriction/modification (RM) systems in vivo; however, the mechanism of inhibition remains unknown. In this study, we showed that recombinant ArdB from Escherichia coli cells co-purified with DNA. When overexpressed in E. coli cells, a portion of ArdB protein formed insoluble DNA-free aggregates. Only native ArdB, but not the ArdBΔD141...

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Identifiers

PMID: 32564736
DOI: 10.1134/S0006297920030074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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