Article
Plasmid-encoded antirestriction protein ArdA can discriminate between type I methyltransferase and complete restriction-modification system.
Journal of molecular biology - 12 Jan 2007
Nekrasov Sergei V, Agafonova Olga V, Belogurova Nataly G, Delver Eugene P, Belogurov Anatol A
Abstract excerpt
Many promiscuous plasmids encode the antirestriction proteins ArdA (alleviation of restriction of DNA) that specifically affect the restriction activity of heterooligomeric type I restriction-modification (R-M) systems in Escherichia coli cells. In addition, a lot of the putative ardA genes encoded by plasmids and bacterial chromosomes are found as a result of sequencing of complete genomic sequences, suggesting...
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