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Article

BRAF and NRAS mutated melanoma: Different Ca2+ responses, Na+/Ca2+ exchanger expression, and sensitivity to inhibitors.

Cell calcium - 1 Sept 2020

Esteves Gabriela Nohemi Nuñez, Ferraz Letícia Silva, Alvarez Marcela Maciel Palacio, Costa Claudia Alves da, Lopes Rayssa de Mello, Tersariol Ivarne Luis Dos Santos, Rodrigues Tiago

Abstract excerpt

Calcium is a ubiquitous intracellular second messenger, playing central roles in the regulation of several biological processes. Alterations in Ca2+ homeostasis and signaling are an important feature of tumor cells to acquire proliferative and survival advantages, which include structural and functional changes in storage capacity, channels, and pumps. Here, we investigated the differences in Ca2+ homeostasis in...

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PMID: 32562975
DOI: 10.1016/j.ceca.2020.102241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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