Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ion channel phenotype of melanoma cell lines.

The Journal of membrane biology - 1 Jan 1997

Allen D H, Lepple-Wienhues A, Cahalan M D

Abstract excerpt

Melanoma cells are transformed melanocytes of neural crest origin. K+ channel blockers have been reported to inhibit melanoma cell proliferation. We used whole-cell recording to characterize ion channels in four different human melanoma cell lines (C8161, C832C, C8146, and SK28). Protocols were used to identify voltage-gated (KV), Ca2+-activated (KCa), and inwardly rectifying (KIR) K+ channels; swelling-sensitive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium Channels
Share to Ion Channel Gating
Share to Melanoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Patch-Clamp Techniques

Share to Phenotype

Share to Potassium Channels

Share to Sodium Channels

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9002422
DOI: 10.1007/s002329900155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ion channel phenotype of melanoma cell lines.PMID 9002422Read ↗

News and views on ion channels in cancer: is cancer a channelopathy?Semantic proximity Read ↗

The rise of T-type channels in melanoma progression and chemotherapeutic resistance.Semantic proximity Read ↗

Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic TherapySemantic proximity Read ↗

BRAF and NRAS mutated melanoma: Different Ca2+ responses, Na+/Ca2+ exchanger expression, and sensitivity to inhibitors.Semantic proximity Read ↗

Voltage-dependent ion channels in CAD cells: A catecholaminergic neuronal line that exhibits inducible differentiation.Semantic proximity Read ↗

The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.Semantic proximity Read ↗

An intracellular anion channel critical for pigmentation.Semantic proximity Read ↗

Involvement of potassium channels in the progression of cancer to a more malignant phenotype.Semantic proximity Read ↗

Studies of ionic mechanisms associated with human cancersSemantic proximity Read ↗

Selected GRIN2A mutations in melanoma cause oncogenic effects that can be modulated by extracellular glutamate.Semantic proximity Read ↗

Novel Protein Kinase C-Mediated Control of Orai1 Function in Invasive Melanoma.Semantic proximity Read ↗

Targeting potassium channels in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.