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Article

Loop-mediated isothermal amplification (LAMP)-based method for detecting factor V Leiden and factor II G20210A common variants.

Journal of thrombosis and thrombolysis - 1 Nov 2020

Luca Tiscia Giovanni, Colaizzo Donatella, Vergura Patrizia, Favuzzi Giovanni, Chinni Elena, Vandermeulen Charlotte, Detemmerman Liselot, Grandone Elvira

Abstract excerpt

Automated methodologies allowing for rapid detection of Factor V Leiden and Factor II G20210A variants are desirable, due to a high number of tested patients. Here, we report a preliminary validation of a CE-marked in vitro diagnostic (IVD) certified method for simultaneous detection of Factor V Leiden and Factor II G20210A variants on whole blood samples. The novel method is based on Loop-mediated isothermal...

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PMID: 32557225
DOI: 10.1007/s11239-020-02183-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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