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Retinoic acid receptor γ activation promotes differentiation of human induced pluripotent stem cells into esophageal epithelium

16 Jun 2020

Abstract excerpt

BACKGROUND: The esophagus is known to be derived from the foregut. However, the mechanisms regulating this process remain unclear. In particular, the details of the human esophagus itself have been poorly researched. In this decade, studies using human induced pluripotent stem cells (hiPSCs) have proven powerful tools for clarifying the developmental biology of various human organs. Several studies using hiPSCs...

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PMID: 32556644
DOI: 10.1007/s00535-020-01695-7

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