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The development and stem cells of the esophagus

15 Mar 2021

Abstract excerpt

The esophagus is derived from the anterior portion of the foregut endoderm, which also gives rise to the respiratory system. As it develops, the esophageal lining is transformed from a simple columnar epithelium into a stratified squamous cell layer, accompanied by the replacement of unspecified mesenchyme with layers of muscle cells. Studies in animal models have provided significant insights into the roles of...

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PMID: 33782045
DOI: 10.1242/dev.193839

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