Article
Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium.
PLoS biology - 1 Jun 2020
Aydin Özge Z, Taflan Sevket Onur, Gurkaslar Can, Firat-Karalar Elif Nur
Abstract excerpt
Centriolar satellites are dynamic, membraneless granules composed of over 200 proteins. They store, modify, and traffic centrosome and primary cilium proteins, and help to regulate both the biogenesis and some functions of centrosomes and cilium. In most cell types, satellites cluster around the perinuclear centrosome, but their integrity and cellular distribution are dynamically remodeled in response to...
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