Article
Interethnic differences in the prevalence of main cardiovascular pharmacogenetic biomarkers.
Pharmacogenomics - 1 Jul 2020
Mirzaev Karin, Abdullaev Sherzod, Akmalova Kristina, Sozaeva Jeannette, Grishina Elena, Shuev Gregory, Bolieva Laura, Sozaeva Mariam, Zhuchkova Svetlana, Gimaldinova Natalya, Sidukova Elena, Serebrova Svetlana, Asoskova Anastasia, Shein Alexander, Poptsova Maria, Suleymanov Salavat, Burashnikova Irina, Shikaleva Anastasia, Kachanova Anastasia, Fedorinov Denis, Sychev Dmitry
Abstract excerpt
Background: The aim of this study was to determine the prevalence of CYP2C9, VKORC1, CYP2C19, ABCB1, CYP2D6 and SLCO1B1 genes polymorphisms among residents of the Volga region (Chuvash and Mari) and northern Caucasus (Kabardins and Ossetians). Materials & methods: The study involved 845 apparently healthy volunteers of both sexes of the four different ethnic groups living in the Russian Federation: 238 from the...
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