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Geriatric fragility fractures are associated with a human skeletal stem cell defect

14 Jun 2020

Abstract excerpt

Fragility fractures have a limited capacity to regenerate, and impaired fracture healing is a leading cause of morbidity in the elderly. The recent identification of a highly purified bona fide human skeletal stem cell (hSSC) and its committed downstream progenitor cell populations provides an opportunity for understanding the mechanism of age-related compromised fracture healing from the stem cell perspective....

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PMID: 32537886
DOI: 10.1111/acel.13164

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