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Rejuvenation of Mesenchymal Stem Cells to Ameliorate Skeletal Aging

24 Mar 2023

Abstract excerpt

Advanced age is a shared risk factor for many chronic and debilitating skeletal diseases including osteoporosis and periodontitis. Mesenchymal stem cells develop various aging phenotypes including the onset of senescence, intrinsic loss of regenerative potential and exacerbation of inflammatory microenvironment via secretory factors. This review elaborates on the emerging concepts on the molecular and epigenetic...

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PMID: 37048071
DOI: 10.3390/cells12070998

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