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Concise Review: Musculoskeletal Stem Cells to Treat Age-Related Osteoporosis

18 Aug 2017

Abstract excerpt

Age-related (type-II) osteoporosis is a common and debilitating condition driven in part by the loss of bone marrow (BM) mesenchymal stromal cells (MSC) and their osteoblast progeny, leading to reduced bone formation. Current pharmacological regiments targeting age-related osteoporosis do not directly treat the disease by increasing bone formation, but instead use bisphosphonates to reduce bone resorption-a...

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PMID: 28834263
DOI: 10.1002/sctm.17-0054

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