Article

Mechanical Rejuvenation of Mesenchymal Stem Cells from Aged Patients

2024-06-09

Abstract excerpt

Mesenchymal stem cells (MSC) are an appealing therapeutic cell type for many diseases. However, patients with poor health or advanced age often have MSCs with poor regenerative properties. A major limiter of MSC therapies is cellular senescence, which is marked by limited proliferation capability, diminished multipotency, and reduced regenerative properties. In this work, we explored the ability of applied mechani...

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Literature Corpus work: 3a60d621-5e79-507b-84e4-4b601a3ec256
DOI: 10.1101/2024.06.06.597781

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