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Article

Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence

19 Feb 2022

Abstract excerpt

More than 2.1 million age-related fractures occur in the United States annually, resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of bone structure is associated with impaired bone healing. Fracture healing is a dynamic process which can be divided into four stages. While the initial hematoma generates an inflammatory environment in which mesenchymal stem cells and...

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PMID: 35182420
DOI: 10.1210/endrev/bnac008

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