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Type 1 diabetes genetic risk score is discriminative of diabetes in non-Europeans: evidence from a study in India.

Scientific reports - 11 Jun 2020

Harrison James W, Tallapragada Divya Sri Priyanka, Baptist Alma, Sharp Seth A, Bhaskar Seema, Jog Kalpana S, Patel Kashyap A, Weedon Michael N, Chandak Giriraj R, Yajnik Chittaranjan S, Oram Richard A

Abstract excerpt

Type 1 diabetes (T1D) is a significant problem in Indians and misclassification of T1D and type 2 diabetes (T2D) is a particular problem in young adults in this population due to the high prevalence of early onset T2D at lower BMI. We have previously shown a genetic risk score (GRS) can be used to discriminate T1D from T2D in Europeans. We aimed to test the ability of a T1D GRS to discriminate T1D from T2D and...

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PMID: 32528078
DOI: 10.1038/s41598-020-65317-1
PMCID: PMC7289794

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