Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of CCM Phenotype by a Human Microvascular Endothelial Model.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020

Delle Monache Simona, Retta Saverio Francesco

Abstract excerpt

Cerebral cavernous malformations (CCMs) is a disorder of endothelial cells predominantly localized in the brain. Although a complete inactivation of each CCM protein has been found in the affected endothelium of diseased patients and a necessary and additional role of microenvironment has been demonstrated to determine in vivo the occurrence of vascular lesions, a microvascular endothelial model based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Disease Susceptibility
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Hemangioma, Cavernous, Central Nervous System

Share to Microtubule-Associated Proteins

Share to Phenotype

Share to Transfection

Source

Identifiers

PMID: 32524549
DOI: 10.1007/978-1-0716-0640-7_10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of CCM Phenotype by a Human Microvascular Endothelial Model.PMID 32524549Read ↗

Endothelial cell disease: emerging knowledge from cerebral cavernous malformationsSemantic proximity Read ↗

Isolation of Cerebral Endothelial Cells from CCM1/KRIT1 Null Mouse Brain.Semantic proximity Read ↗

From Genes and Mechanisms to Molecular-Targeted Therapies: The Long Climb to the Cure of Cerebral Cavernous Malformation (CCM) Disease.Semantic proximity Read ↗

Molecular and Cellular Characterization of Primary Endothelial Cells from a Familial Cavernomatosis PatientSemantic proximity Read ↗

Study of CCM Microvascular Endothelial Phenotype by an In Vitro Tubule Differentiation Model.Semantic proximity Read ↗

Molecular Genetic Features of Cerebral Cavernous Malformations (CCM) Patients: An Overall View from Genes to Endothelial Cells.Semantic proximity Read ↗

Cerebral cavernous malformations as a disease of vascular permeability: from bench to bedside with caution.Semantic proximity Read ↗

Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations.Semantic proximity Read ↗

Endothelial Differentiation of CCM1 Knockout iPSCs Triggers the Establishment of a Specific Gene Expression SignatureSemantic proximity Read ↗

Cerebral Cavernous Malformation Pathogenesis: Investigating Lesion Formation and Progression with Animal Models.Semantic proximity Read ↗

Recent insights into cerebral cavernous malformations: the molecular genetics of CCM.Semantic proximity Read ↗

CRISPR/Cas9-mediated Generation of Human Endothelial Cell Knockout Models of CCM Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.