Generation of CCM Phenotype by a Human Microvascular Endothelial Model.

doi:10.1007/978-1-0716-0640-7_10

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Generation of CCM Phenotype by a Human Microvascular Endothelial Model.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020

Delle Monache Simona, Retta Saverio Francesco

Abstract excerpt

Cerebral cavernous malformations (CCMs) is a disorder of endothelial cells predominantly localized in the brain. Although a complete inactivation of each CCM protein has been found in the affected endothelium of diseased patients and a necessary and additional role of microenvironment has been de...

Topics

Biomarkers
Cell Culture Techniques
Disease Susceptibility
Endothelial Cells
Endothelium, Vascular
Gene Expression
Gene Knockdown Techniques
Hemangioma, Cavernous, Central Nervous System
Humans
KRIT1 Protein
Microtubule-Associated Proteins
Phenotype
RNA, Small Interfering
Transfection

Source

Open in PubMed

Identifiers

PMID: 32524549
DOI: 10.1007/978-1-0716-0640-7_10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-32524549-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics