Article
Planning and Analysis of Axon Degeneration Screening Experiments.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Lovell Lyndah, Bramley John, Buchser William
Abstract excerpt
A network of intersecting molecular pathways interacts to initiate and execute axon destruction. Maximum protection against axon degeneration likely requires more than manipulation of a single target. Here, we describe the process of designing a high-throughput arrayed screening assay for the identification of key factors responsible for axon destruction and/or protection. First, we go over some existing screens...
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