Article

Exploring SARM1 as a target to delay programmed axon degeneration

2021-01-01

Abstract excerpt

Programmed axon degeneration (Wallerian degeneration) can occur after physical injury, inhibition of axon transport, exposure to neurotoxic compounds, and in diseases involving mitochondrial or metabolic dysfunction. There is increasing evidence that this pathway can be activated in human painful neuropathies and preclinical evidence suggests it is also active in neurodegenerative conditions, such as Parkinson’s d...

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Literature Corpus work: 683e0fce-3362-5ce1-b043-d56be2b2072a
DOI: 10.17863/cam.63179

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