Article
The definition and global epidemiology of nonmobile colistin resistance (NMCR-3) determinants in Aeromonas from 1968 to 2022.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Nov 2023
Yu Keyi, Huang Zhenzhou, Xiao Yue, Bai Xuemei, Gao He, Wang Duochun
Abstract excerpt
Polymyxins are the last line of defense in infections caused by multidrug-resistant Gram-negative bacteria. The chromosomal EptA in Aeromonas genus was defined as a nonmobile colistin resistance determinant 3 (NMCR-3). A total of 14 NMCR-3 genotypes were identified. The global prevalence of Aeromonas-borne NMCRs and MCRs indicates an increasing trend from 1968 to 2022. And an index of resistance risk, i.e, the...
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