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Association ofSOD3 promoter DNA methylation with its down-regulation in breast carcinomas

8 Jun 2020

Abstract excerpt

Superoxide dismutase 3 (SOD3) is a secreted antioxidant enzyme that regulates reactive oxygen species in the microenvironment. It is also a potential tumour suppressor gene that is significantly downregulated in breast cancer. We have previously shown that its mRNA expression is inversely correlated with relapse free survival in breast cancer patients. This study aimed to investigate the correlation of SOD3...

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PMID: 32508251
DOI: 10.1080/15592294.2020.1777666

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