Article
Foxp3 promoter polymorphism (rs3761548) in breast cancer progression: a study from India.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2014
Jahan Parveen, Ramachander V R Vinish, Maruthi G, Nalini S, Latha K Prasanna, Murthy T S R
Abstract excerpt
Breast cancer is the most common female neoplasm that drives the transformation of normal mammary epithelial cells into highly malignant derivatives. Forkhead Box Protein3 (Foxp3), a tumor suppressor/immunomodulatory gene, which controls the function of Treg cells and oncogenes is down regulated in breast cancer. The main aim of the present study is to evaluate the potential influence of Foxp3-3279 C>A...
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