Article
Genetic polymorphisms of NOS3 are associated with the risk of invasive breast cancer with lymph node involvement.
Breast cancer research and treatment - 1 Dec 2007
Lee Kyoung-Mu, Choi Ji-Yeob, Lee Jong Eun, Noh Dong-Young, Ahn Sei-Hyun, Han Wonshik, Yoo Keun-Young, Hayes Richard B, Kang Daehee
Abstract excerpt
Endothelial nitric oxide synthase (NOS3) produces nitric oxide which is a mediator of cytotoxic effects potentially associated with breast cancer. We evaluated the role of genetic polymorphisms of NOS3 in breast cancer etiology, in a case-control study conducted in Korea. We recruited 1,385 eligi...
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