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Article

Genetic locus responsible for diabetic phenotype in the insulin hyposecretion (ihs) mouse.

PloS one - 1 Jan 2020

Nakano Kenta, Yanobu-Takanashi Rieko, Shimizu Yukiko, Takahashi Yuki, Hiura Koki, Watanabe Masaki, Sasaki Hayato, Okamura Tadashi, Sasaki Nobuya

Abstract excerpt

Diabetic animal models have made significant contributions to understanding the etiology of diabetes and to the development of new medications. Our research group recently developed a novel diabetic mouse strain, the insulin hyposecretion (ihs)mouse. The strain involves neither obesity nor insulitis but exhibits notable pancreatic β-cell dysfunction, distinguishing it from other well-characterized animal models....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32502168
DOI: 10.1371/journal.pone.0234132
PMCID: PMC7274380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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