Article
Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation.
Fertility and sterility - 1 May 2013
Finch Amy, Valentini Adriana, Greenblatt Ellen, Lynch Henry T, Ghadirian Parviz, Armel Susan, Neuhausen Susan L, Kim-Sing Charmaine, Tung Nadine, Karlan Beth, Foulkes William D, Sun Ping, Narod Steven
Abstract excerpt
OBJECTIVE: To evaluate the impact of carrying a BRCA1 or BRCA2 mutation on the probability of experiencing premature natural menopause. DESIGN: Observational study. SETTING: Patients in an academic research environment. PATIENT(S): Women who carry a BRCA1 or BRCA2 mutation (case subjects) and women who do not carry a mutation (control subjects). INTERVENTION(S): Survey about reproductive history administered on...
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