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Protein QTL analysis of IGF-I and its binding proteins provides insights into growth biology.

Human molecular genetics - 29 Aug 2020

Bartell Eric, Fujimoto Masanobu, Khoury Jane C, Khoury Philip R, Vedantam Sailaja, Astley Christina M, Hirschhorn Joel N, Dauber Andrew

Abstract excerpt

The growth hormone and insulin-like growth factor (IGF) system is integral to human growth. Genome-wide association studies (GWAS) have identified variants associated with height and located near the genes in this pathway. However, mechanisms underlying these genetic associations are not understood. To investigate the regulation of the genes in this pathway and mechanisms by which regulation could affect growth,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32484228
DOI: 10.1093/hmg/ddaa103
PMCID: PMC7471503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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