Article

Protein QTL analysis of IGF-I and its binding proteins provides insights into growth biology

2020-03-26

Abstract excerpt

The growth hormone and insulin-like growth factor (IGF) system is integral to human growth. Genome-wide association studies (GWAS) have identified variants associated with height and located near the genes in this pathway. However, mechanisms underlying these genetic associations are not understood. To investigate the regulation of the genes in this pathway and mechanisms by which regulation could affect growth, w...

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Literature Corpus work: a1e30bf6-5fd2-50d8-aa1b-c2cead95e4e0
DOI: 10.1101/2020.03.25.007724

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