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Article

Associations of insulin-like growth factor binding protein-3 gene polymorphisms with IGF-I activity and lipid parameters in adolescents.

International journal of obesity (2005) - 1 Dec 2009

Mong J L Y, Ng M C Y, Guldan G S, Tam C H T, Lee H M, Ma R C W, So W Y, Wong G W K, Kong A P S, Chan J C N, Waye M M Y

Abstract excerpt

OBJECTIVE: Childhood obesity is a growing global epidemic. Recent studies indicate that obesity and related metabolic traits are highly heritable. Increasing evidence suggests that growth hormone (GH) and the insulin-like growth factor-I (IGF-I) axis have important functions in regulating adiposity and insulin sensitivity. Five single-nucleotide polymorphisms (SNPs) at IGF-binding protein-3 (IGFBP3) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19786971
DOI: 10.1038/ijo.2009.186

Genes

IGFBP3

Provenance

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