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Article

Mapping quantitative trait loci for serum insulin-like growth factor-1 levels in mice.

Bone - 1 Oct 2000

Rosen C J, Churchill G A, Donahue L R, Shultz K L, Burgess J K, Powell D R, Ackert C, Beamer W G

Abstract excerpt

Serum insulin-like growth factor-1 (IGF-1) and femoral bone mineral density (BMD) differ between two inbred strains of mice, C3H/HeJ (C3H) and C57BL/6J (B6), by approximately 30% and 50%, respectively. Similarly, skeletal IGF-1 content, bone formation, mineral apposition, and marrow stromal cell numbers are higher in C3H than in B6 mice. Because IGF-1 and several bone parameters cosegregate, we hypothesize that...

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PMID: 11033447
DOI: 10.1016/s8756-3282(00)00354-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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