Article
CopomuS-Ranking Compensatory Mutations to Guide RNA-RNA Interaction Verification Experiments.
International journal of molecular sciences - 28 May 2020
Raden Martin, Gutmann Fabio, Uhl Michael, Backofen Rolf
Abstract excerpt
In silico RNA-RNA interaction prediction is widely applied to identify putative interaction partners and to assess interaction details in base pair resolution. To verify specific interactions, in vitro evidence can be obtained via compensatory mutation experiments. Unfortunately, the selection of compensatory mutations is non-trivial and typically based on subjective ad hoc decisions. To support the decision...
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