Article
corRna: a web server for predicting multiple-point deleterious mutations in structural RNAs.
Nucleic acids research - 1 Jul 2011
Lam Edmund, Kam Alfred, Waldispühl Jérôme
Abstract excerpt
RNA molecules can achieve a broad range of regulatory functions through specific structures that are in turn determined by their sequence. The prediction of mutations changing the structural properties of RNA sequences (a.k.a. deleterious mutations) is therefore useful for conducting mutagenesis experiments and synthetic biology applications. While brute force approaches can be used to analyze single-point...
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