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Article

Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn's disease.

World journal of gastroenterology - 14 May 2020

Elleisy Nagi, Rohde Sarah, Huth Astrid, Gittel Nicole, Glass Änne, Möller Steffen, Lamprecht Georg, Schäffler Holger, Jaster Robert

Abstract excerpt

BACKGROUND: Crohn's disease (CD) is characterized by a multifactorial etiology and a significant impact of genetic traits. While NOD2 mutations represent well established risk factors of CD, the role of other genes is incompletely understood. AIM: To challenge the hypothesis that single nucleotide polymorphisms (SNPs) in the genes CLEC5A and CLEC7A, two members of the C-type lectin domain family of pattern...

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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotyping Techniques

Share to Lectins, C-Type

Share to Leukocytes, Mononuclear

Share to Nod2 Signaling Adaptor Protein

Share to Polymorphism, Single Nucleotide

Share to Receptors, Cell Surface

Source

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Identifiers

PMID: 32476786
DOI: 10.3748/wjg.v26.i18.2194
PMCID: PMC7235209

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