Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis.

doi:10.1111/cas.14507

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Article

Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis.

Cancer science - 1 Aug 2020

Suda Kazuaki, Cruz Diaz Luis Antonio, Yoshihara Kosuke, Nakaoka Hirofumi, Yachida Nozomi, Motoyama Teiichi, Inoue Ituro, Enomoto Takayuki

Abstract excerpt

Clear cell carcinoma of the ovary is thought to arise from endometriosis. In addition, retrograde menstruation of shed endometrium is considered the origin of endometriosis. However, little evidence supports cellular continuity from uterine endometrium to clear cell carcinoma through endometriosis at the genomic level. Here, we performed multiregional whole-exome sequencing to clarify clonal relationships among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32473611
DOI: 10.1111/cas.14507
PMCID: PMC7419022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.