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Ovarian Clear Cell Carcinoma: Genomic Characterization, Pathogenesis and Targeted Therapy

26 Jul 2023

Abstract excerpt

Ovarian clear cell carcinomas (OCCCs) are a subtype of ovarian epithelial tumors that arise from the malignant transformation of endometriosis (EMs). These tumors have distinctive molecular features, high malignant potential, low sensitivity to conventional chemotherapy, and poor prognosis. The process and mechanism of malignant transformation from EMs to OCCCs remains elusive. Elucidation of the molecular...

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PMID: 37500149
DOI: 10.21873/anticanres.16515

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