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Article

Elucidating the pathogenesis of synchronous and metachronous tumors in a woman with endometrioid carcinomas using a whole-exome sequencing approach.

Cold Spring Harbor molecular case studies - 1 Nov 2017

Wu Ren-Chin, Veras Ema, Lin Jeffrey, Gerry Emily, Bahadirli-Talbott Asli, Baras Alexander, Ayhan Ayse, Shih Ie-Ming, Wang Tian-Li

Abstract excerpt

Synchronous endometrial and ovarian (SEO) carcinomas involve endometrioid neoplasms in both the ovary and uterus at the time of diagnosis. Patients were traditionally classified as having independent primary SEO lesions or as having metastatic endometrioid carcinoma. Recent studies have supported that SEO tumors result from the dissemination of cells from one organ site to another. However, whether this can be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29162652
DOI: 10.1101/mcs.a001693
PMCID: PMC5701312

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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