Article
Targeted next-generation sequencing for molecular diagnosis of endometriosis-associated ovarian cancer.
Journal of molecular medicine (Berlin, Germany) - 1 Jul 2016
Er Tze-Kiong, Su Yu-Fa, Wu Chun-Chieh, Chen Chih-Chieh, Wang Jing, Hsieh Tsung-Hua, Herreros-Villanueva Marta, Chen Wan-Tzu, Chen Yi-Ting, Liu Ta-Chih, Chen Hung-Sheng, Tsai Eing-Mei
Abstract excerpt
UNLABELLED: Recent molecular and pathological studies suggest that endometriosis may serve as a precursor of ovarian cancer (endometriosis-associated ovarian cancer, EAOC), especially of the endometrioid and clear cell subtypes. Accordingly, this study had two cardinal aims: first, to obtain mutation profiles of EAOC from Taiwanese patients; and second, to determine whether somatic mutations present in EAOC can...
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