Article
Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases.
American journal of human genetics - 4 Jun 2020
González Juan R, Ruiz-Arenas Carlos, Cáceres Alejandro, Morán Ignasi, López-Sánchez Marcos, Alonso Lorena, Tolosana Ignacio, Guindo-Martínez Marta, Mercader Josep M, Esko Tonu, Torrents David, González Josefa, Pérez-Jurado Luis A
Abstract excerpt
The burden of several common diseases including obesity, diabetes, hypertension, asthma, and depression is increasing in most world populations. However, the mechanisms underlying the numerous epidemiological and genetic correlations among these disorders remain largely unknown. We investigated whether common polymorphic inversions underlie the shared genetic influence of these disorders. We performed an...
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