Article
The fat tail of obesity as told by the genome.
Current opinion in clinical nutrition and metabolic care - 1 Jul 2008
Herbert Alan
Abstract excerpt
PURPOSE OF REVIEW: Many genes affect pathways that predispose to and protect against obesity. We ask how many different variants affect human obesity and how common are they? RECENT FINDINGS: The current generation of genome-wide association scans is moderately powered to detect and replicate associations between single nucleotide polymorphisms, or common copy number variations and common diseases. They are not...
Topics
- Environment
- Epigenesis, Genetic
- Female
- Genetic Variation
- Genome, Human
- Humans
- Male
- Obesity
- Polymorphism, Single Nucleotide
- Pregnancy
- Prenatal Exposure Delayed Effects