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Role of cell cycling and polyploidy in placental trophoblast of different mammalian species

29 May 2020

Abstract excerpt

The trophoblast cells that take part in placenta formation are characterized by different modes of multiplication of their genome that largely designates their eu- or aneuploidy level. The two main ways of genome multiplication are described in different degree: (a) endoreduplication that involves almost complete shutdown of mitosis and (b) reduced mitosis ('endomitosis') in which, by contrast, entry into mitosis...

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PMID: 32470192
DOI: 10.1111/rda.13732

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