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Article

Giant and binucleate trophoblast cells of mammals

1 Sept 1993

Abstract excerpt

The cellular origin, structure, and function of trophoblastic giant cells (GC) and binucleate cells (BNC) are reviewed. Mammals in which these cells have received the greatest attention include rodents, rabbits, and humans (GCs), and ruminants and equids (BNCs). In almost all cases these cells arise from the cytotrophoblast. All are large cells and contain either two diploid nuclei (BNCs), multiple nuclei (human...

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PMID: 8371098
DOI: 10.1002/jez.1402660607

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