Detecting Ethambutol Resistance in Mycobacterium tuberculosis Isolates in China: A Comparison Between Phenotypic Drug Susceptibility Testing Methods and DNA Sequencing of embAB

Abstract excerpt

With the increasing incidence of drug-resistant tuberculosis (TB), determining a rapid and accurate drug susceptibility testing (DST) method to identify ethambutol (EMB) resistance in Mycobacterium tuberculosis (M. tuberculosis) has become essential for patient management in China. Herein we evaluated the correlation between three phenotypic DST methods, namely proportion method (PM), MGIT 960 system, and...

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