Article
A rapid quantification of invasive phenotype in head and neck squamous cell carcinoma: A novel 3D pillar array system.
Oral oncology - 1 Sept 2020
Choi Sung Yong, Lee Dong Woo, Song Bokhyun, Kim Soo Yoon, Kim Hye Jin, Shin Da-Yong, Ku Bosung, Chung Man Ki
Abstract excerpt
BACKGROUND: The widely used in vitro invasion assays for head and neck squamous cell carcinoma (HNSCC) are wound healing, transwell, and organotypic assays. However, these are still lab-intensive and time-consuming tasks. For the rapid detection and high throughput screening of invasiveness in 3D condition, we propose a novel spheroid invasion assay using commercially available pillar platform system. MATERIALS...
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