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Generation of uniform-sized spheroids using PDMS-based microwell devices as 3D cancer models for pharmacological profiling of drugs

2025-09-04

Abstract excerpt

Cancer researchers now consider spheroids a valuable in vitro model for cancer research and personalized medicine. They are used to studying cancer development, testing drug effectiveness, and potentially guiding treatment decisions for individual patients. Spheroids represent the simplest form of three-dimensional (3D) cellular arrangement and encapsulate the essential tumor microenvironment. These characteristic...

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Literature Corpus work
d5d9b9a9-4eb9-5000-9767-9375498104e3
DOI
10.1101/2025.09.01.673452
Open publication

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Generation of uniform-sized spheroids using PDMS-based microwell devices as 3D cancer models for pharmacological profiling of drugsDOI 10.1101/2025.09.01.673452
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