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A Head and Neck Cancer Spheroid Model for Phenotypic High-Content Screening of Chemoresistance.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Wandrey Madita, Khamis Hassan Aya, Stauber Roland H, Gül Désirée

Abstract excerpt

Resistance against common treatment regimens like chemotherapy is a major concern in current cancer research and clinical disease management. Moreover, in vitro cell culture models cannot always adequately represent the tumor situation in vivo, hampering the analysis of the underlying mechanisms. Efforts have been made to establish three-dimensional (3D) cancer cell models, such as spheroids or organoids,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Drug Screening Assays, Antitumor

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Share to Spheroids, Cellular

Share to Squamous Cell Carcinoma of Head and Neck

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Identifiers

PMID: 41479057
DOI: 10.1007/978-1-0716-4985-5_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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