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Article

Sentinel surveillance of the WHO-validated Pfkelch13 C580Y artemisinin resistance marker in Plasmodium falciparum isolates from Bangui, Central African Republic

2026-05-04

Abstract excerpt

<title>Abstract</title> <p>Background Artemisinin-based combination therapies (ACTs) are the cornerstone of malaria treatment. However, partial artemisinin resistance associated with mutations in the Plasmodium falciparum kelch13 (pfk13) propeller domain threatens malaria control efforts. The C580Y substitution is the principal World Health Organization (WHO) validated molecular marker for resistance surveillanc...

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Literature Corpus work
bfad8cf3-f5a0-5d65-88db-c7a6c766084c
DOI
10.21203/rs.3.rs-9399260/v1
Open publication

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Sentinel surveillance of the WHO-validated Pfkelch13 C580Y artemisinin resistance marker in Plasmodium falciparum isolates from Bangui, Central African RepublicDOI 10.21203/rs.3.rs-9399260/v1
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