Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progression.

Journal of dermatological science - 1 Jun 2020

Villani Rehan, Sim Seen Ling, Roy Edwige, Wainwright Brandon, Francois Mathias, Khosrotehrani Kiarash

Abstract excerpt

BACKGROUND: Basal Cell Carcinoma is the most common tumour and yet much remains to be determined regarding the molecular mechanisms that leads to its development. Hedgehog signal activation is sufficient for BCC induction, but the molecular mediators of BCC growth are not well understood. SoxF transcription factor Sox18 has been identified in human BCC, but its role in growth of the tumour is as yet unknown....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Basal Cell
Share to Epidermis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hedgehog Proteins

Share to Patched-1 Receptor

Share to Receptors, Notch

Share to Severity of Illness Index

Share to Skin Neoplasms

Share to SOXF Transcription Factors

Source

Identifiers

PMID: 32444239
DOI: 10.1016/j.jdermsci.2020.04.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progression.PMID 32444239Read ↗

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion.Semantic proximity Read ↗

Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development.Semantic proximity Read ↗

Expression of human SOX18 in normal tissues and tumors.Semantic proximity Read ↗

SOX4 reversibly induces phenotypic changes by suppressing the epithelial marker genes in human keratinocytes.Semantic proximity Read ↗

TBX1 and Basal Cell Carcinoma: Expression and Interactions with Gli2 and Dvl2 SignalingSemantic proximity Read ↗

SOX9 and SOX10 but Not BRN2 Are Required for Nestin Expression in Human Melanoma CellsSemantic proximity Read ↗

Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanomaSemantic proximity Read ↗

Construction and functional analysis of novel dominant-negative mutant of human SOX18 protein.Semantic proximity Read ↗

Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes.Semantic proximity Read ↗

Differential allele loss on chromosome 9q22.3 in human non-melanoma skin cancer.Semantic proximity Read ↗

Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin.Semantic proximity Read ↗

Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.