Article
Expression of human SOX18 in normal tissues and tumors.
International journal of molecular medicine - 1 Sept 2002
Saitoh Tetsuroh, Katoh Masaru
Abstract excerpt
SOX proteins are a family of transcription factors with high-mobility-group DNA-binding domain (HMG box) homologous to SRY, which play key roles in embryogenesis. Xenopus Sox17alpha, Sox17beta, Sox3 and mouse Sox7 are reported to be negative regulators of the WNT-beta-catenin-TCF signaling pathway. SOX7, SOX17, and SOX18 constitute a subfamily among the SOX gene family. Here, expression of SOX18 mRNA was...
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